Recombinant Human CXCL16 (E. coli)
Cat. No. | Z102385 |
Name | Recombinant Human CXCL16 (E. coli) |
Description |
Chemokine (CXC motif) ligand 16, is a small cytokine belonging to the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 is composed of its typical CXC chemokine domain, a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail which allow CXCL16 to act as a cell surface bound molecule as well as a soluble chemokine. Human CXCL16 shares 70% amino acid sequence similarity with the mouse and CXCL16 expression is induced by IFN-γ and TNF-α. CXCL16 is produced by dendritic cells in lymphoid organs, and by red pulp spleen cells. The expression of CXCL16 may attract lymphocytes during inflammation and assist some immune responses. |
Organism | Human (H. sapiens) |
Unit quantity | 25 µg |
Family | Chemokine-alpha Family (CXC) |
Aliases | Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16, transmembrane chemokine CXCL16 |
Gene Symbol | CXCL16 |
Gene ID | 58191 |
Accession Number | Q9H2A7 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 10.4 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 µm filtered solution in PBS |
Function | The ED50 is 2.5-12 ng/mL as determined by its ability to chemoattract activated lymphocytes (at a concentration of 100.0 ng/mL) |
Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102385 |
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product: