Recombinant Human CXCL16 (E. coli)

Cat. No.
Z102385
Unit
25 µg
Price
$205.00
Cat. No. Z102385
Name Recombinant Human CXCL16 (E. coli)
Description

Chemokine (CXC motif) ligand 16, is a small cytokine belonging to the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 is composed of its typical CXC chemokine domain, a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail which allow CXCL16 to act as a cell surface bound molecule as well as a soluble chemokine. Human CXCL16 shares 70% amino acid sequence similarity with the mouse and CXCL16 expression is induced by IFN-γ and TNF-α. CXCL16 is produced by dendritic cells in lymphoid organs, and by red pulp spleen cells. The expression of CXCL16 may attract lymphocytes during inflammation and assist some immune responses.

Organism Human (H. sapiens)
Unit quantity 25 µg
Family Chemokine-alpha Family (CXC)
Aliases Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16, transmembrane chemokine CXCL16
Gene Symbol CXCL16
Gene ID 58191
Accession Number Q9H2A7
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 10.4 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in PBS
Function The ED50 is 2.5-12 ng/mL as determined by its ability to chemoattract activated lymphocytes (at a concentration of 100.0 ng/mL)
Reconstitution A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102385
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