Recombinant Human Epiregulin (EREG)

Cat. No.
Z100995
Unit
Price
$246.00
Cat. No. Z100995
Name Recombinant Human Epiregulin (EREG)
Description Epiregulin acts as a local signal mediator and shows dual biological activity, stimulating the proliferation of fibroblasts, hepatocytes, smooth muscle cells, and keratinocytes while also inhibiting the growth of several tumor-derived epithelial cell lines. Epiregulin was first identified in NIH 3T3 cell conditioned medium, and is one of the seven known ligands for the epidermal growth factor receptor (EGFR). Epiregulin is synthesized as a transmembrane precursor before being proteolytically cleaved to release a 46-amino-acid active protein. Epiregulin also shows more potent bioactivity in vitro than other EGF-like growth factors
Organism Human (H. sapiens)
Unit quantity 25 µg
Family EGF Family
Aliases EPR, Proepiregulin, EREG
Gene Symbol EREG
Gene ID 2069
Accession Number O14944
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 6 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Human Epiregulin was lyophilized from a 0.2 μm filtered solution in PBS pH 7.5.
Function The ED(50) was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/mL, corresponding to a specific activity of ≥ 5.0 x 10^5 units/mg.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100995
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

CAT.NO
Z100139
UNIT
1.0 mg
PRICE
$215.00

CAT.NO
Z101455
UNIT
50 µg
PRICE
$52.50

CAT.NO
Z101435
UNIT
50 µg
PRICE
$79.00

CAT.NO
Z100895
UNIT
10 µg
PRICE
$89.00