Recombinant Human FGF17 (E. coli)

Cat. No.
Z102305
Unit
Price
$89.00
Cat. No. Z102305
Name Recombinant Human FGF17 (E. coli)
Description Human FGF17 is a member of the broadly mitogenic FGF family, members of which have key roles in prenatal development, postnatal growth and tissue regeneration. FGF17 has been implicated in the organization and induction of the midbrain/hindbrain junction. It is also found in the developing skeleton, major arteries, heart, tail bud and hindgut, where it is often expressed just following FGF8 expression. While deletion of FGF17 does allow for viable mice, these mice demonstrate abnormalities in areas of the brain and demonstrate abnormal social behaviour. In humans abnormal patterns of FGF17 expression are associated with Dandy-Walker cerebellar malformation as well as a number of types of cancer. Human FGF17 shares 99% sequence similarity with the mouse and rat forms. Recombinant Human FGF17 is a 22.8 kDa heparin binding growth factor.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family FGF Family
Aliases Fibroblast growth factor 17
Gene Symbol FGF17
Gene ID 8822
Accession Number O60258
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 22.8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from 0.2 μm filtered solution in PBS
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102305
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