Recombinant Human FGF18 (E. coli)

Cat. No.
Cat. No. Z102315
Name Recombinant Human FGF18 (E. coli)
Description Human FGF18 is a member of the FGF family, a group of related proteins having broad mitogenic and cell survival activity. Members of this family have key roles in prenatal development, as well as postnatal growth and tissue regeneration. FGF18 promotes chondrogenesis, through interaction with FGFR3. It has been demonstrated to cause an increase in cartilage in a murine osteoarthritis model. It has also been implicated in the proliferation of tissues, notably the liver and small intestine. FGF18 also signals through FGFR 1c, 2c and 4. Recombinant Human FGF18 is a 20.4 kDa heparin binding growth factor.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family FGF Family
Aliases Fibroblast Growth Factor-18, zFGF5
Gene Symbol FGF18
Gene ID 8817
Accession Number O76093
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 20.4 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in phosphate buffer, NaCl, KCl and EDTA (pH 7.5)
Function The bioactivity was determined in a 3T3 cell proliferation assay. The ED50 was in the range of 0.05 - 0.1 ng/ml.
Reconstitution A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. Please note, filter sterilization is a must following reconstitution. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102315
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Controls and Related Product:

1.0 mg

50 µg

50 µg

10 µg