Recombinant Human FGF21 (E. coli)
Cat. No. | Z101105 |
Name | Recombinant Human FGF21 (E. coli) |
Description | FGF21 is a secreted growth factor of the FGF family, classified as an FGF19 subfamily member. Proteins of the FGF family are known to play a central role with respect to both prenatal and postnatal growth and development, and regeneration of a variety of tissues by promoting cellular proliferation and differentiation. In the presence of beta Klotho (protein cofactor), FGF21 signals via the FGFR receptors to stimulate insulin independent glucose uptake by adipocytes. |
Organism | Human (H. sapiens) |
Unit quantity | 20 µg |
Family | FGF Family |
Aliases | dJ881L22.2, FIT2 |
Gene Symbol | FGF21 |
Gene ID | 26291 |
Accession Number | Q9NSA1 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 19.7 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from 0.2 μm filtered solution in Tris and NaCl (pH 8.0) |
Function | The bioactivity was determined in a NIH/3T3 cell proliferation assay with an ED50 <1ng/ml. |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101105 |
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