Recombinant Human Follistatin (FST)

Cat. No.
Z101035
Unit
Price
$246.00
Cat. No. Z101035
Name Recombinant Human Follistatin (FST)
Description Expressed in the pituitary, ovaries, and in some other tissues, FST is a high affinity activin binding protein that can act as an activin antagonist. FST was originally discovered through its suppressive effect of the expression and secretion of the pituitary follicle stimulating hormone. Besides activin, FS has also been shown to bind with multiple BMPs, Myostatin, GDF-11, and TGF-beta-1. Human Follistatin contains three cysteine-rich domains (called Follistatin-like domains), 3 Kazal-like domains and one TGF-beta binding domain.
Organism Human (H. sapiens)
Unit quantity 10 µg
Family Other Growth Factors/Cytokines
Aliases FS, Activin-binding protein
Gene Symbol FST
Gene ID 10468
Accession Number P19883
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 31 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant Human Follistatin was lyophilized at 1.0 mg/mL containing no additives.
Function The ED(50) was determined by the ability to neutralize Activin A inhibitory effect of mouse MPC-11 cells and was determined to be 0.1-0.4 µg/mL in the presence of 7.5 ng/mL Activin A.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101035
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