Recombinant Human HB-EGF (Heparin Binding EGF) (E. coli)

Cat. No.
Z102155
Unit
Price
$89.00
Cat. No. Z102155
Name Recombinant Human HB-EGF (Heparin Binding EGF) (E. coli)
Description Human HBEGF (Heparin Binding EGF like growth factor) is a member of the EGF family of peptide growth factors that signal through the EGF receptor, and stimulates the proliferation of smooth muscle cells, fibroblasts, epithelial cells, and keratinocytes. HBEGF is expressed in many cell types and tissues, including bronchial epithelium, visceral and vascular smooth muscle, CD4+ T cells, glomerular podocytes, keratinocytes, macrophages and certain tumor cells. Mature HBEGF is a soluble peptide that arises from the proteolytic processing of the 208 amino acid type-I transmembrane form and exhibits the ability to specifically bind heparin and heparin sulfate proteoglycans.
Organism Human (H. sapiens)
Unit quantity 50 µg
Family EGF Family
Aliases Heparin Binding EGF-like growth factor, HBEGF, Diphtheria toxin receptor, DTR
Gene Symbol HBEGF
Gene ID 1839
Accession Number Q99075
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 10.1 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Function The ED50, as determined by a cell proliferation assay (using balb/c 3T3 cells) is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Reconstitution It is recommended to reconstitute HBEGF in sterile PBS at 250 μg/mL.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102155
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

CAT.NO
Z100139
UNIT
1.0 mg
PRICE
$215.00

CAT.NO
Z101455
UNIT
50 µg
PRICE
$52.50

CAT.NO
Z101435
UNIT
50 µg
PRICE
$79.00

CAT.NO
Z100895
UNIT
10 µg
PRICE
$89.00