Recombinant Human IFNB1

Cat. No.
Cat. No. Z101485
Name Recombinant Human IFNB1
Description IFN-beta is produced mainly by fibroblasts and some epithelial cell types. The synthesis of IFN-beta can be induced by common inducers of interferons including viruses, double-stranded RNA, and micro-organisms. It is induced also by some cytokines such as TNF and IL-1. IFN-beta binds to the same receptor as IFN-alpha. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. IFN-beta increases the expression of HLA class 1 antigens and blocks the expression of HLA class 2 antigens stimulated by IFN-gamma. IFN-beta stimulates the activity of natural killer cells and hence also antibody-dependent cytotoxicity. IFN-beta shows antiproliferative activity against a number of cell lines established from solid tumors.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family IL-10/Interferon Family
Aliases IFN-beta, Immune interferon, Fibroblast interferon, Leukocyte interferon, B cell interferon, Type I interferon
Recombinant Human Interferon-Beta 1A (IFNB1)
Gene Symbol IFNB1
Gene ID 3456
Accession Number P01574
Source CHO cells
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 19 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant IFN-b 1a was lyophilized from a 0.2 μm filtered sodium acetate solution pH 4.8.
Function The activity was determined by the viral resistance assay of Human WISH cells was found to be in the range of 3.0 x 10^8 IU/mg.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101485
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

1.0 mg

50 µg

50 µg

10 µg