Recombinant Human IGF2 (E. coli)

Cat. No.
Z102345
Unit
Price
$52.50
Cat. No. Z102345
Name Recombinant Human IGF2 (E. coli)
Description Insulin-like growth factor 2 (IGF2) is one of the mitogenic, polypeptide growth factors that belongs to the insulin family, due to its structural and functional similarity to insulin. IGF2 is mainly produced in the liver and several other tissues at certain times. IGF2 expression can be found in many tissues usually with autocrine, paracrine and endocrine functions. IGF2 mainly acts as a growth promoting hormone during gestation, and does so by binding to the tyrosine kinase type I receptor (IGF1R) as well as the IGF2 receptor cation-independent mannose 6-phosphate receptor. Mature IGF2 is highly conserved between human, bovine, and porcine species. Recombinant Human IGF2 is a single, non-glycosylated, polypeptide chain of 7.8 kDa.
Organism Human (H. sapiens)
Unit quantity 10 µg
Family IGF/Insulin Family
Aliases Insulin-like growth factor II, multiplication stimulating activity, MSA, Somatomedin-A, T3M-11-derived growth factor, PP1446
Gene Symbol IGF2
Gene ID 3481
Accession Number P01344
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 7.8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in Tris and NaCl
Function The ED50 as determined by dose dependent proliferation of MCF7 cells was <1ng/ml
Reconstitution Reconstitute in sterile PBS at 100 µg/mL
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102345
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