Recombinant Human IL17D (E. coli)

Cat. No.
Z102425
Unit
Price
$52.50
Cat. No. Z102425
Name Recombinant Human IL17D (E. coli)
Description

Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.

Organism Human (H. sapiens)
Unit quantity 5 µg
Family IL-17 Family
Aliases

Interleukin-27

Gene Symbol IL17D
Gene ID 53342
Accession Number Q8TAD2
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 20.5 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation 20 mM Phosphate, pH 7.5, 150 mM NaCl
Function The ED50 was determined by a cell proliferation assay using human T cell line and found to be <0.2ng/ml.
Reconstitution

Reconstitute in sterile 4mM HCl at 100µg/mL (containing at least 0.1% human or bovine serum albumin)

Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102425
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