Recombinant Human IL17D (E. coli)
Cat. No. | Z102425 |
Name | Recombinant Human IL17D (E. coli) |
Description |
Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells. |
Organism | Human (H. sapiens) |
Unit quantity | 5 µg |
Family | IL-17 Family |
Aliases | IL-17D |
Gene Symbol | IL17D |
Gene ID | 53342 |
Accession Number | Q8TAD2 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 20.5 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | 20 mM Phosphate, pH 7.5, 150 mM NaCl |
Function | The ED50 was determined by a cell proliferation assay using human T cell line and found to be <0.2ng/ml. |
Reconstitution |
Reconstitute in sterile 4mM HCl at 100µg/mL (containing at least 0.1% human or bovine serum albumin) |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102425 |
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