Recombinant Human IL22 (E. coli)

Cat. No.
Z100945
Unit
Price
$89.00
Cat. No. Z100945
Name Recombinant Human IL22 (E. coli)
Description Originally identified as a gene induced by IL-9 in mouse T cells and mast cells, IL-22 is a member of the IL-10 family of cytokines. IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the pancreas and liver. The IL-22 receptor complex consists of two receptor subunits, IL-22R and IL-10R-beta that belong to the class II cytokine receptor family. Recombinant human IL-22 is a non-disulfide-linked homodimeric protein.
Organism Human (H. sapiens)
Unit quantity 10 µg
Family IL-10/Interferon Family
Aliases IL-22, IL-TIF, Cytokine Zcyto18, IL-10-related T cell-derived-inducible factor, ILTIF, ZCYTO18
Recombinant Human Interleukin-22 (IL22)
Gene Symbol IL22
Gene ID 50616
Accession Number Q9GZX6
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 17 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant Interleukin-22 was lyophilized from 0.2 μm filtered concentrated (1.0 mg/mL) solution in 500 mM NaCl, 20 mM Tris, pH 8.0.
Function Activity was determined by the ability to inhibit growth of human A549 cancer cells at concentrations ranging between 50-100 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100945
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