Recombinant Human IL29 (IFNL1)

Cat. No.
Z100505
Unit
Price
$246.00
Cat. No. Z100505
Name Recombinant Human IL29 (IFNL1)
Description The IFN-lambda gene family is composed of three distinct genes: IFN-lambda1 (IL-29), IFN-lambda2 (IL-28A), and IFN-lambda3 (IL-28B). IFN-lambda proteins exhibit only weak homology to IL-10, but, like IL-10, they also use the IL-10R2 chain as a component of their receptor complex. The IFN-receptor complex consists of the unique ligand-binding chain IFN- R. The IFN-lambda-1 gene is found exclusively in primate genomes and is 81% identical to IFN-lambda-2/3. IFN-lambda-s, which are now collectively referred to as type III IFNs, exhibit several features in common with type I IFNs, such as antiviral, antiproliferative, and antitumor activities.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family IL-10/Interferon Family
Aliases Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, IL-29
Recombinant Human Interleukin-29 (IFNL1)
Gene Symbol IFNL1
Gene ID 282618
Accession Number Q8IU54
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 20 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered 20 mM PBS,130 mM NaCl solution pH 7.5
Function The ED(50) is determined in an anti-viral assay using human HepG2 cells infected with EMCV is typically 1-5 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100505
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