Recombinant Human IL36RN (IL1F5) (E. coli)

Cat. No.
Z102645
Unit
Price
$89.00
Cat. No. Z102645
Name Recombinant Human IL36RN (IL1F5) (E. coli)
Description Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family IL-1 Family
Aliases IL36RN FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, Interleukin-36 receptor antagonist protein
Gene Symbol IL36RN
Gene ID 26525
Source E. coli
Species Human (H. sapiens)
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and KCl
Reconstitution A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. This solution can then be diluted into other buffers.
Storage This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102645
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