Recombinant Human LEC (CCL16)

Cat. No.
Z100325
Unit
Price
$246.00
Cat. No. Z100325
Name Recombinant Human LEC (CCL16)
Description CCL16 is a CC chemokine that specifically attracts lymphocytes, dendritic cells, and monocytes; increases their adhesive properties and has myelosuppressive activity. It is constitutively expressed in liver and is increased by interleukin 10 (IL-10) in activated monocytes. CCL16 is present in human plasma suggesting that it may be active outside hepatic tissue. CCR1, CCR2, CCR5, and CCR8 are the functional receptors of this chemokine.
Organism Human (H. sapiens)
Unit quantity 25 µg
Family Chemokine-beta Family (CC)
Aliases C-C motif chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-inducible chemokine, LCC-1, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant, Monotactin-1, MNT-1, NCC-4, Small-inducible cytokine A16, CCL16, ILINCK, NCC4, SCYA16
Gene Symbol CCL16
Gene ID 6360
Accession Number O15467
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 11 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered 20 mM PBS, 100 mM NaCl solution pH 7.5
Function Determined by its ability to chemoattract human monocytes using a concentration range of 2.0-40 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100325
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