Recombinant Human Maspin (SerpinB5) (E. coli)

Cat. No.
Z102505
Unit
Price
$126.00
Cat. No. Z102505
Name Recombinant Human Maspin (SerpinB5) (E. coli)
Description Mammary serine protease inhibitor (Maspin) is a non-inhibitory tumor suppressor serpin that is encoded by the SERPINB5 gene. Playing an important role in embryonic development in cell adhesion, Maspin has the ability to suppress the growth, invasion, and metastasis of breast and lung tumors. However, Maspin does not exhibit any serine protease inhibitor activity since it does not undergo the conformational transition from stressed to relaxed found in typical serpins. It is expressed in normal breast and prostatic epithelial cells, but downregulated in most breast carcinoma.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Somatotropin/Sclerostin/Serpin Families
Aliases Maspin, Peptidase inhibitor 5
Gene Symbol SERPINB5
Gene ID 5268
Accession Number P36952
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 42.3 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Function The ED(50) was determined by the dose-dependent proliferation of MDA-MB-468 cells and was found to be <0.05ng/mL.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102505
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