Recombinant Human MEC (CCL28)

Cat. No.
Z101025
Unit
Price
$246.00
Cat. No. Z101025
Name Recombinant Human MEC (CCL28)
Description The mucosa-associated epithelial chemokine CCL28 is a common mucosal chemokine which is constitutively expressed by epithelial cells in most mucosal sites. Both CCL28 and CCL25 have recently been shown to be essential for lymphocyte migration to gastrointestinal tissues. CCL28 attracts IgA ASC, but not IgG or IgM ASC, from both intestinal and extraintestinal mucosal tissue, while CCL25 preferentially attracts IgA ASC from the small intestine and its draining lymphoid tissues, as well as alpha-4-beta-7(+) T cells.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Chemokine-beta Family (CC)
Aliases C-C motif chemokine 28, CCL28, MEC, Protein CCK1, Small-inducible cytokine A28, SCYA28
Recombinant Human Mucosae-Associated Epithelial Chemokine (CCL28)
Gene Symbol CCL28
Gene ID 56477
Accession Number Q9NRJ3
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 12 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant CCL-28 was lyophilized from PBS pH 7.4.
Function Determined by the ability to chemoattract human lymphocytes using a concentration range of 2-10 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101025
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