Recombinant Human MIP-3 alpha (CCL20)

Cat. No.
Z100705
Unit
Price
$246.00
Cat. No. Z100705
Name Recombinant Human MIP-3 alpha (CCL20)
Description Macrophage inflammatory protein (MIP)-3/CCL20, also known as liver and activation-regulated chemokine (LARC) or Exodus, is a member of the CC chemokine subfamily initially noted to be expressed in human liver, lung, appendix, and tonsillar crypts. MIP-3 is selectively chemotactic for CD34(+) bone marrow cell-derived immature DCs and CD45RO(+) memory T cells that express the cognate receptor CCR6. MIP-3 produced at sites of inflammation may chemoattract CCR6-expressing immature DCs to the subepithelial region of mucosal surfaces.
Organism Human (H. sapiens)
Unit quantity 25 µg
Family Chemokine-beta Family (CC)
Aliases Beta-chemokine exodus-1, MIP3 alpha, CC chemokine LARC, Liver and activation-regulated chemokine, MIP-3-alpha, Small-inducible cytokine A20, SCYA20
Recombinant Human Macrophage Inflammatory Protein-3 Alpha (CCL20)
Gene Symbol CCL20
Gene ID 6364
Accession Number P78556
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant CCL20 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5.
Function Determined by its ability to chemoattract human monocytes using a concentration range of 2-40 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100705
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