Recombinant Human MIP-3 (CCL23) (E. coli)

Cat. No.
Z100695
Unit
Price
$89.00
Cat. No. Z100695
Name Recombinant Human MIP-3 (CCL23) (E. coli)
Description CCL23 (MPIF-1, CK8, SCYA23), a member of the CC chemokine family, was originally isolated from a human aortic endothelial cell library and from the human monocytic cell line THP-1. It is most closely related to MIP-1 and interacts with its receptor CCR1, which is expressed on monocytes, dendritic cells, lymphocytes, and endothelial cells. Functionally, CCL23 has chemotactic activity for monocytes, DC, lymphocytes, neutrophils, osteoclast precursor cells, and endothelial cells. In contrast, CCL23 reduces the proliferation of progenitor cells giving rise to granulocyte and monocyte lineages, whereas it enhances angiogenesis of endothelial cells
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Chemokine-beta Family (CC)
Aliases CK-beta-8, CKB-8, MIP3, Myeloid progenitor inhibitory factor 1, MPIF-1, Small-inducible cytokine A23, MIP3, MPIF1, SCYA23, CCL23, C-C motif chemokine 23
Recombinant Human Macrophage Inflammatory Protein-3 (CCL23)
Gene Symbol CCL23
Gene ID 6368
Accession Number P55773
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 11 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant CCL23 was lyophilized from a 0.2 μm filtered 20 mM PB, 100 mM NaCl solution pH 7.5.
Function Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100695
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