Recombinant Human MIP-4 (CCL18) (E. coli)
Cat. No.
Z100715
Unit
Price
$92.00
| Cat. No. | Z100715 |
| Name | Recombinant Human MIP-4 (CCL18) (E. coli) |
| Description | CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38 mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma. |
| Organism | Human (H. sapiens) |
| Unit quantity | 10 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases | AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18 |
| Gene Symbol | CCL18 |
| Gene ID | 6362 |
| Accession Number | P55774 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Recombinant CC18 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5. |
| Function | Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100715 |
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