Recombinant Human MIP-4 (CCL18) (E. coli)

Cat. No.
Z100715
Unit
Price
$89.00
Cat. No. Z100715
Name Recombinant Human MIP-4 (CCL18) (E. coli)
Description CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38 mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma.
Organism Human (H. sapiens)
Unit quantity 10 µg
Family Chemokine-beta Family (CC)
Aliases MIP4, CCL18, Pulmonary and activation-regulated chemokine, PARC, DC-CK1, AMAC-1, C-C motif chemokine 18, Small-inducible cytokine A18
Recombinant Human Macrophage Inflammatory Protein-4 (CCL18)
Gene Symbol CCL18
Gene ID 6362
Accession Number P55774
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant CC18 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5.
Function Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100715
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