Recombinant Human NRG4 (E. coli)

Cat. No.
Cat. No. Z100905
Name Recombinant Human NRG4 (E. coli)

Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.

Organism Human (H. sapiens)
Unit quantity 50 µg
Family Other Growth Factors/Cytokines

Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG4
Recombinant Human Neuregulin-4 (NRG4)

Gene Symbol NRG4
Gene ID 145957
Accession Number Q8WWG1
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 7 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method

>95% as determined by SDS-PAGE

Formulation Lyophilized from a 0.2 μm filtered PBS, pH 7.4 solution.
Function The ED(50) was determined by the dose-dependent proliferation of Raji cells and was found to be <0.05ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100905
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