Recombinant Human NRG4 (E. coli)
Cat. No. | Z100905 |
Name | Recombinant Human NRG4 (E. coli) |
Description |
Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells. |
Organism | Human (H. sapiens) |
Unit quantity | 50 µg |
Family | Other Growth Factors/Cytokines |
Aliases |
Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG4 |
Gene Symbol | NRG4 |
Gene ID | 145957 |
Accession Number | Q8WWG1 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 7 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity |
>95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 μm filtered PBS, pH 7.4 solution. |
Function | The ED(50) was determined by the dose-dependent proliferation of Raji cells and was found to be <0.05ng/mL. |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100905 |
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.