Recombinant Human Persephin (PSPN) (E. coli)

Cat. No.
Z102495
Unit
Price
Inquiry
Cat. No. Z102495
Name Recombinant Human Persephin (PSPN) (E. coli)
Description Persephin is a disulfide-linked homodimeric neurotrophic factor belonging to the Transforming Growth Factor-beta (TGF-beta) superfamily and the GDNF sub-family. One cysteine residue, out of the seven conserved, is used for inter-chain disulfide bridging while the others form a cysteine knot ring formation. It signals through RET and one of the four GFR-alpha (alpha-1, alpha-2, alpha-3, alpha-4) receptors to promote the proper development and maintenance of the nervous system. Persephin promotes survival of dopaminergic neurons in the midbrain as well as some motor neurons, and promotes branching of ureteric buds.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family TGF-beta Super-family
Aliases PSP
Gene Symbol PSPN
Gene ID 5623
Accession Number O60542
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 10.7 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)
Function The ED50 is 4.0-16.0 ng/mL as determined by a cell proliferation assay
Reconstitution Reconstitute in sterile 4mM HCl at 100µg/mL (containing at least 0.1% human or bovine serum albumin)
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102495
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

CAT.NO
Z100139
UNIT
1.0 mg
PRICE
$215.00

CAT.NO
Z101455
UNIT
50 µg
PRICE
$52.50

CAT.NO
Z101435
UNIT
50 µg
PRICE
$79.00

CAT.NO
Z100895
UNIT
10 µg
PRICE
$89.00