Recombinant Human sCD23 (FCER2) (E. coli)

Cat. No.
Z101835
Unit
Price
$246.00
Cat. No. Z101835
Name Recombinant Human sCD23 (FCER2) (E. coli)
Description CD23 is a calcium dependent transmembrane glycoprotein which is expressed in many cell types. The cytoplasmic region of the protein has two isoforms the 'a' isoform that participates in IgE-regulated endocytosis, and the 'b' isoform, which is involved in IgE-regulated phagocytosis. It has been found that there are at least four soluble forms of the CD23 protein (sCD23) all of which are produced by the activity of metallo/cysteine proteases. In addition to binding IgE, sCD23 have been shown to promote the activation and differentiation of B-cells and stimulate the release of pro-inflammatory cytokines from monocytes.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Other Growth Factors/Cytokines
Aliases Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, B cell differentiation antigen
Recombinant Human C-type Lectin Domain Family 4 Member J (FCER2)
Gene Symbol FCER2
Gene ID 2208
Accession Number P06734
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 19.5 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in PBS
Function Measured by its ability to bind in a functional ELISA. Immobilized rhCD23 at 2 µg/mL (100 µL/well) can bind human IgE with a linear range of 0.015­1 µg/mL.
Reconstitution Reconstitute at 100 µg/mL in sterile PBS
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101835
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