Recombinant Human TGF Beta-1 (TGFB1)

Cat. No.
Z101555
Unit
20 µg
Price
$535.00
Cat. No. Z101555
Name Recombinant Human TGF Beta-1 (TGFB1)
Description TGFB1 is the prototype member of the TGF-beta super-family that includes Inhibins, Activin A, MIS (Müllerian inhibiting substance), BMP (bone morphogenetic proteins), dpp (decapentaplegic) and Vg-1. TGFB1 is the most potent known growth inhibitor for normal and transformed epithelial cells, endothelial cells, fibroblasts, neuronal cells, lymphoid cells and other hematopoietic cell types. TGF-beta inhibits the proliferation of T lymphocytes by down-regulating predominantly IL2 mediated proliferative signals and also inhibits the growth of natural killer cells. Recombinant human TGFB1 is a disulfide linked homodimer protein that migrates at approximately 26kDa under non-reducing conditions.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family TGF-beta Super-family
Aliases Transforming growth factor beta-1, TGF-beta-1, Differentiation inhibiting factor, Latency-associated peptide, LAP
Gene Symbol TGFB1
Gene ID 7040
Accession Number P01137
Source HEK293 cells
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 26 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from 0.2 μm filtered PBS solution pH 7.4
Function The ED50 as determined by the ability to inhibit the proliferation of mink lung epithelial cells was found to be in the range of 0.05-0.1 ng/ml
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101555
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