Recombinant Human TSLP (E. coli)

Cat. No.
Z101095
Unit
Price
$89.00
Cat. No. Z101095
Name Recombinant Human TSLP (E. coli)
Description TSLP is a hemopoietic protein that was initially identified from mouse thymic stromal cell line that promoted the development of B cells. TSLP overlaps biological activities with IL-7 and can co-stimulate growth of thymocytes and mature T cells alongside supporting lymphopoiesis. Human TSLP shares approximately 43% amino acid sequence identity with mouse TSLP. Human TSLP has been detected in many tissues although the highest level of expression has been found in the heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex that consists of IL-7R-alpha and the TSLP-R.
Organism Human (H. sapiens)
Unit quantity 10 µg
Family Other Growth Factors/Cytokines
Aliases Thymic stromal lymphopoietin, TSLP
Recombinant Human Thymic Stromal Lymphopoietin (TSLP)
Gene Symbol TSLP
Gene ID 85480
Accession Number Q969D9
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 15 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Human TSLP was Lyophilized from a 0.2 μm filtered concentrated (1.0 mg/mL) solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Function The ED(50) was determined by the dose-dependent proliferation of human IL-7R-alpha and human TSLP R co-transfected mouse BaF3 cells, was found to be < 3.0 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101095
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