Recombinant Human TWEAK (TNFSF12) (E. coli)
Cat. No. | Z102275 |
Name | Recombinant Human TWEAK (TNFSF12) (E. coli) |
Description | TWEAK is a TNF superfamily transmembrane protein which is expressed in many different cells and tissues, such as the heart, spleen and small intestine. Two different receptors have been identified that bind TWEAK; the Death Receptor 3 (DR3) and the TWEAK Receptor (TWEAKR). While DR3 is expressed mainly in tissues that have high concentration of lymphocytes, the mitogen-inducible TWEAKR is has been shown to be expressed in fibroblasts, hepetocellular carcinomas and endothelial cells. Recombinant human TWEAK comprises the TNF homologous (secreted region) of TWEAK. |
Organism | Human (H. sapiens) |
Unit quantity | 25 µg |
Family | TNF Super-family |
Aliases | TWE-PRIL |
Gene Symbol | TNFSF12 |
Gene ID | 407977 |
Accession Number | O43508 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 17.2 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein |
Reconstitution | Reconstitute at 0.1mg/ml/mL in sterile PBS containing at least 0.1% human or bovine serum albumin |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102275 |
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