Recombinant Mouse Eotaxin (CCL11) (E. coli)
Cat. No. | Z200035 |
Name | Recombinant Mouse Eotaxin (CCL11) (E. coli) |
Description | Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils. |
Organism | Mouse (M. musculus) |
Unit quantity | 20 µg |
Family | Chemokine-beta Family (CC) |
Aliases | C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11, SCYA11 |
Gene Symbol | CCL11 |
Gene ID | 20292 |
Accession Number | P48298 |
Source | E. coli |
Species | Mouse (M. musculus) |
Appearance | Lyophilized Powder |
Molecular Weight | 8 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS |
Function | Activity was determined by the ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-20 ng/mL. |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z200035 |
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