Recombinant Mouse Exodus-2 (CCL21A)
Cat. No. | Z200045 |
Name | Recombinant Mouse Exodus-2 (CCL21A) |
Description | Exodus-2 has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. Exodus-2 selectively stimulates the chemotaxis of adult T-lymphocytes and is expressed preferentially in lymph node tissue. Exodus-2 is critical for adult T-cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T cell trafficking through nodal tissue. |
Organism | Mouse (M. musculus) |
Unit quantity | 20 µg |
Family | Chemokine-beta Family (CC) |
Aliases | C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a, Thymus-derived chemotactic agent 4, TCA4, Scya21, Scya21a, Ccl21a |
Gene Symbol | CCL21A |
Gene ID | 65956 |
Accession Number | P84444 |
Source | E. coli |
Species | Mouse (M. musculus) |
Appearance | Lyophilized Powder |
Molecular Weight | 12 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
Purity | >95% as determined by SDS-PAGE |
Formulation | Recombinant mouse Exodus-2 was lyophilized from a 0.2 μm filtered PBS solution. |
Function | Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/mL. |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z200045 |
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