Recombinant Mouse G-CSF (CSF3) (E. coli)

Cat. No.
Z200605
Unit
10 µg
Price
$372.00
Cat. No. Z200605
Name Recombinant Mouse G-CSF (CSF3) (E. coli)
Description

Granulocyte colony-stimulating factor (G-CSF) is a growth factor and cytokine belonging to the IL-6 family of interleukins. It is produced by a variety of cells such as: endothelial cells, bone marrow stroma, macrophages, fibroblasts, and other immune cells in response to endotoxin activation. G-CSF stimulates the bone marrow to stimulate the survival, proliferation and differentiation of progenitor cells to mature neutrophils while enhancing its activities. It indirectly mobilizes stem cells by downregulating the expression of CXCL12 on marrow osteoblasts and releases neutrophil and monocyte proteolytic enzymes. Mouse G-CSF affects mouse skeletal muscle development by activating proliferation of myoblasts. Human and murine G-CSF shares a 73% amino acid identity and is cross-reactive.

Organism Mouse (M. musculus)
Unit quantity 10 µg
Family IL-6 Family
Aliases Granulocyte colony-stimulating factor
Gene Symbol CSF3
Gene ID 12985
Accession Number P09920
Source E. coli
Species Mouse (M. musculus)
Appearance Lyophilized Powder
Molecular Weight 19.2 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in PBS
Function The ED50 was 10.0-60.0 pg/mL as determined by a cell proliferation assay
Reconstitution Reconstitute in sterile deionized water at 100 µg/mL
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z200605
Print & Download Datasheet
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

CAT.NO
Z100139
UNIT
1.0 mg
PRICE
$215.00

CAT.NO
Z101455
UNIT
50 µg
PRICE
$52.50

CAT.NO
Z101435
UNIT
50 µg
PRICE
$79.00

CAT.NO
Z100895
UNIT
10 µg
PRICE
$89.00