Recombinant Mouse KGF (FGF7) (E. coli)

Cat. No.
Z200185
Unit
Price
$89.00
Cat. No. Z200185
Name Recombinant Mouse KGF (FGF7) (E. coli)
Description KGF is a member of the family of fibroblast growth factors, it is secreted in large amounts by fibroblast- like stromal cells in epithelial tissues. The KGF receptor encodes a tyrosine kinase and is a member of the family of receptors binding aFGF and bFGF. Binding of KGF to its receptor is competed by aFGF and bFGF. Although KGF is a potent specific mitogen for many epithelial cells it is not so for fibroblasts and endothelial cells. KGF is thought to play an important role in the paracrine growth control of normal epithelial cells. KGF stimulates the proliferation of primary and secondary human keratinocytes to the same extent as EGF.
Organism Mouse (M. musculus)
Unit quantity 10 µg
Family FGF Family
Aliases KGF, Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7
Recombinant Mouse Keratinocyte Growth Factor (FGF7)
Gene Symbol FGF7
Gene ID 14178
Accession Number P36363
Source E. coli
Species Mouse (M. musculus)
Appearance Lyophilized Powder
Molecular Weight 19 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in PBS
Function The ED(50) was determined by the dose-dependent proliferation of Immortalized Human Bronchial Epithelial Cells-SV40 and was found to be <0.05ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z200185
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